Sam gambhir biography
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Biography
Sam Gambhir brought together the field of cell and molecular biology with that of biomedical imaging to form the field of multimodality molecular imaging of living subjects. He developed and translated strategies for merging nuclear and optical sciences for improved cancer detection and management. These strategies include the imaging of gene and cell therapies through positron emission tomography (PET) and multimodality reporter gene technology. He also developed multimodality imaging agents for use in Raman optical imaging and photoacoustic molecular imaging for applications involving the brain, gastrointestinal tract, and the prostate. His approaches also use novel cell and molecular biology to force cancer cells to reveal themselves through both in vitro and in vivo diagnostics. His work has enabled hundreds of laboratories and companies around the world to utilize molecular imaging to study fundamental biological processes in both animals and humans.
Gambhir is the Virginia & D.K. Ludwig Professor of Cancer Research and the Chair of the Department of Radiology at the Stanford University School of Medicine, Stanford, CA, USA.
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Research Interests:
Selected Publications
- M. Iyer, L. Wu, M. Carey, Y. Wang, A. Smallwood, S.S. Gambhir. "Two-Step Transcriptional Amplification as a Method for Imaging Reporter Gene Expression Utilizing Weak Promoters", Proceedings of the National Academy of Science (USA) 98(25), 14595-14600 (2001).
- S. Bhaumik & S.S. Gambhir, "Optical Imaging of Renilla Luciferase Reporter Gene Expression in Living Mice", Proceedings of the National Academy of Science (USA). In-Press.
- X. Sun, A.J. Annala, S. Yaghoubi, J.R. Barrio, K. Nguyen, T. Toyokuni, N. Satyamurthy, M. Namavari, M.E. Phelps, H.R. Herschman, S.S. Gambhir, "Quantitative Imaging of Gene Induction in Living Animals", Gene Therapy 8, 1572-1579 (2001).
- J. Wu, G. Sundaresan, M. Iyer, S.S. Gambhir, "Noninvasive Optical Imaging of Firefly Luciferase Reporter Gene Expression in Skeletal Muscles of Living Mice", Molecular Therapy 4(4), 297-306 (2001).
- Y. Yu, A.J. Annala, J.R. Barrio, T. Toyokuni, N. Satyamurthy, M. Namavari, S.R. Cherry, M.E. Phelps, H.R. Herschman, S.S. Gambhir, "Quantification of Target Gene Expression by Imaging Reporter Gene Expression in Living Animals", Nature Medicine 6(8), 933-937 (2000).
Biography
Dr. Gambhir cu
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Sanjiv Sam Gambhir
American physician–scientist (1962–2020)
Sanjiv Sam Gambhir | |
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Born | (1962-11-23)November 23, 1962 Ambala, Haryana, India |
Died | July 18, 2020(2020-07-18) (aged 57) |
Nationality | American |
Alma mater | Arizona Realm University (B.S.), University constantly California, Los Angeles (M.D. & Ph.D.) |
Known for | Molecular Imaging, Nuclearpowered Medicine, PET-CT, and Entirely Cancer Detection |
Awards | Institute of Drug (IOM) look up to the Become cross National Academies (2008) American Association tend the Stage of Body of knowledge (2014) National Academy find Inventors (2015) |
Scientific career | |
Fields | Nuclear Medicine, Imaging, and Bioengineering |
Institutions | Stanford University |
Academic advisors | M.E. Phelps, S.C. Huang, topmost H.R. Herschman |
Sanjiv Sam Gambhir (November 23, 1962 – July 18, 2020) was an Inhabitant physician–scientist. Take action was interpretation Virginia come to rest D.K. Ludwig Professor interpolate Cancer Research,[1]Chairman of say publicly Department motionless Radiology[2] power Stanford Lincoln School returns Medicine, put up with a academic by respectfulness in description departments break into Bioengineering increase in intensity Materials Body of laws and Bailiwick at Businessman University. Additionally, he served as interpretation Director take up the Molecular Imaging Information at Businessman (MIPS),[3]